Studies: People Who Have Already Had COVID Don’t Need the Same Vaccine Regimen
Studies indicate that those who have already had COVID-19 may only need one dose of the new vaccine.
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Two new studies have shown that only one dose of the vaccine, instead of the traditional two, would be sufficient to boost antibodies and fight the coronavirus in the nearly 30 million people in the United States who have already had it.
The new research sums up the findings of two others published over the past few weeks, which indicate that people who have had COVID-19 should be immunized, but a single dose may be enough.
Immunologist Jennifer Gommerman explained:
“I think it’s a really strong rationale for why people who were previously infected with COVID should be getting the vaccine.”
After they have been infected with the virus, most people produce antibodies that can last for many months, but others who had mild or no symptoms of the disease produce few antibodies.
Gommerman said the vaccines “even the playing field”, meaning that those recovered from the virus can produce enough antibodies to protect against reinfection.
The new study was published by medRxiv, and it has not yet been peer-reviewed the blood samples from those recovered from COVID-19.
Immunologist and leader of the study, Andrew McGuire, explained that these studies suggest that immune systems had trouble fighting a new variant of the virus, but one dose of the vaccine gave them “a massive, massive boost”.
He said:
“It looks pretty clear that we’re boosting their pre-existing immunity.”
One shot of either the Pfizer-BioNTech or Moderna vaccine elevated the number of antibodies in the blood by a thousandfold and helped the body to fight off the new variant.
Apoorva Mandavilli wrote:
“In fact, the antibodies seemed to perform better than those in people who had not had Covid and had received two doses of a vaccine.”
While scientists are still unsure of the duration of the increased amount of antibodies, McGuire said “hopefully, they’ll last a long time.”
Another study, led by immunologist Dr. Florian Krammer, found that people who recovered from COVID-19 and received a single dose of the vaccine experienced severe side effects and had more antibodies compared to someone who had not been infected.
Krammer reported:
“If you put all four papers together, that’s providing pretty good information about people who already had an infection only needing one vaccination.”
New research has also shown that Pfizer’s vaccine generates strong immunity after a single dose.
A peer-reviewed Israeli government-owned Sheba Medical Center study suggests that a single shot of the vaccine is 85 percent effective in preventing disease after 15-28 days.
Eyal Leshem, study author and director of Sheba’s Center for Travel Medicine and Tropical Diseases, said:
“This is the first study assessing effectiveness of a single vaccine dose in real-life conditions and shows early effectiveness, even before the second dose was administered.”
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Source: www.nytimes.com
